# Research Object Crate for DRC_biochemical_toECBD

Original URL: https://workflowhub.eu/workflows/389/ro_crate?version=1

This workflow can be used to fit dose-response curves from normalised biochemical assay data (%Inhibition) using the HCS extension. This workflow needs R-Server to run in the back-end. Start R and run the following command: library(Rserve); Rserve(args = "--vanilla") IC50 values will not be extrapolated outside the tested concentration range For activity classification the following criteria are applied: - maximum (average % inhibion) >25 % and slope is >0 and IC50 > 5 µM or - minimum (average % inhibion) >75 % Results are formatted for upload to the European Chemical Biology Database (ECBD)

Author
  Jeanette Reinshagen
License
  CC-BY-4.0

## Contents

Main Workflow: DRC_biochemical_toECBD
Size: 10087717 bytes
Main Workflow Diagram: DRC_template_biochemical.PNG
Size: 49286 bytes