Teams

The members of the Applied Computational Biology group at the Institute of Experimental Genetics (IEG) at the Helmholtz Zentrum München (HMGU) cover a wide range of scientific disciplines, all possessing deep IT knowledge and experience and a strong command of the IT toolbox. As a team, we work at the interface between biology and applied computer sciences in our institute as well as in external collaborations.

The ACCR group headed by Prof. Dr. Florian Rambow focuses on resolving and perturbing cancer cell fate decisions to prevent cancer progression and therapy resistance. We leverage the power of spatially resolved single-cell approaches in combination with computational biology to investigate cell state plasticity and the contribution of the tumor microenvironment. Our primary aim is to advance translational precision oncology.

Team of contributors working on the ARA (Automated Record Analysis) pipeline.ARA is an automatic pipeline for exploration of SRA datasets with sequences as a query.

Dr. Ferhat Ay and his lab are currently located at the La Jolla Institute of Immunology. Our lab focuses on the study of the 3D genome including the development of statistical tools to better interrogate functions and associations between the 3D genome and other biological factors.